CD9

CD9

CD9
Identificadores
Símbolo CD9
Símbolos alt. 5H9; BA2; BTCC-1; DRAP-27; GIG2; MIC3; MRP-1; P24; TSPAN29
Entrez 928
HUGO 1709
OMIM 143030
RefSeq NM_001769
UniProt P21926
Otros datos
Locus Cr. 12 p13

En inmunología se denomina CD9 (del inglés cluster of differentiation) a un tipo de antígeno CD propio del sistema inmune de mamíferos. Se caracteriza por poseer un peso molecular de 24 kDa y su naturaleza bioquímica lo encuadra dentro de la familia de proteínas transmembrana que atraviesan la bicapa cuatro veces. Su función biológica en la célula es: mediar en la agregación plaquetaria y la activación vía FcγIIa y, se postula, podría intervenir en la migración celular. Se expresa específicamente en células pre-B, monocitos, eosinófilos, basófilos, plaquetas, células T activadas, nervios periféricos y cerebrales y músculo liso vascular.[1]

Referencias

  1. Janeway, Jr et al (2000). Inmunobiología. Masson, SA. ISBN 84-458-1176-2.

Publicaciones científicas relacionadas

  • Berditchevski F (2002). «Complexes of tetraspanins with integrins: more than meets the eye.» J. Cell. Sci.. Vol. 114. n.º Pt 23. pp. 4143-51. PMID 11739647.
  • Boucheix C, Benoit P, Frachet P, et al. (1991). «Molecular cloning of the CD9 antigen. A new family of cell surface proteins.» J. Biol. Chem.. Vol. 266. n.º 1. pp. 117-22. PMID 1840589.
  • Benoit P, Gross MS, Frachet P, et al. (1991). «Assignment of the human CD9 gene to chromosome 12 (region P13) by use of human specific DNA probes.» Hum. Genet.. Vol. 86. n.º 3. pp. 268-72. PMID 1997380.
  • Lanza F, Wolf D, Fox CF, et al. (1991). «cDNA cloning and expression of platelet p24/CD9. Evidence for a new family of multiple membrane-spanning proteins.» J. Biol. Chem.. Vol. 266. n.º 16. pp. 10638-45. PMID 2037603.
  • Higashihara M, Takahata K, Yatomi Y, et al. (1990). «Purification and partial characterization of CD9 antigen of human platelets.» FEBS Lett.. Vol. 264. n.º 2. pp. 270-4. PMID 2358073.
  • Ikeyama S, Koyama M, Yamaoko M, et al. (1993). «Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA.» J. Exp. Med.. Vol. 177. n.º 5. pp. 1231-7. PMID 8478605.
  • Rubinstein E, Benoit P, Billard M, et al. (1993). «Organization of the human CD9 gene.» Genomics. Vol. 16. n.º 1. pp. 132-8. DOI 10.1006/geno.1993.1150PMID 8486348.
  • Radford KJ, Thorne RF, Hersey P (1996). «CD63 associates with transmembrane 4 superfamily members, CD9 and CD81, and with beta 1 integrins in human melanoma.» Biochem. Biophys. Res. Commun.. Vol. 222. n.º 1. pp. 13-8. DOI 10.1006/bbrc.1996.0690PMID 8630057.
  • Schmidt C, Künemund V, Wintergerst ES, et al. (1996). «CD9 of mouse brain is implicated in neurite outgrowth and cell migration in vitro and is associated with the alpha 6/beta 1 integrin and the neural adhesion molecule L1.» J. Neurosci. Res.. Vol. 43. n.º 1. pp. 12-31. DOI 10.1002/jnr.490430103PMID 8838570.
Obtenido de "CD9"

Wikimedia foundation. 2010.

Mira otros diccionarios:

  • CD9 — molecule Identifiers Symbols CD9; BTCC 1; DRAP 27; FLJ99568; MIC3; MRP 1; TSPAN 29; TSPAN29 External IDs …   Wikipedia

  • CD9 — Молекула CD9 Обозначения Символы CD7; BA2, MRP 1, P24, TSPAN29 Entrez Gene …   Википедия

  • CD9 — Code 9 it means parents are around …   Glossary of chat acronyms & text shorthand

  • cd9 — Code 9 (other people nearby) …   Glossary of chat acronyms & text shorthand

  • CD63 — Молекула CD63 Обозначения Символы CD63; LAMP 3; ME491; MLA1; OMA81H; TSPAN30 Entrez Gene …   Википедия

  • CD53 — CD53, also known as Cluster of Differentiation 53, is a human gene.cite web | title = Entrez Gene: CD53 CD53 molecule| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=963| accessdate = ] PBB Summary section… …   Wikipedia

  • CD63 — CD63, also known as Cluster of Differentiation 63, is a human gene.cite web | title = Entrez Gene: CD63 CD63 molecule| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=967| accessdate = ] PBB Summary section… …   Wikipedia

  • CD82 (gene) — CD82 (Cluster of Differentiation 82) is a human protein encoded by the gene|CD82 gene.cite web | title = Entrez Gene: CD82 CD82 molecule| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=3732| accessdate = ]… …   Wikipedia

  • PTGFRN — Prostaglandin F2 receptor negative regulator, also known as PTGFRN, is a human gene.cite web | title = Entrez Gene: PTGFRN prostaglandin F2 receptor negative regulator| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • A Low Hum — is an on going concert tour in New Zealand s and is important for rising bands and alternative music groupsFact|date=February 2008. It was founded by professional photographer and music impresario Blink (born Ian Jorgensen), and is based in… …   Wikipedia


Compartir el artículo y extractos

Link directo
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.